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Antibodies

Anti-Kinetochore protein NDC80 homolog [Hec1 (9G3)]

Product Sizes
1 mg
Was £2163.00 £2055.00
AB03500-1-1-BT-1MG
About this Product
SKU:
AB03500-1-1-BT
Additional Names:
NDC80; HEC; HEC1; KNTC2; Highly expressed in cancer protein; Kinetochore protein Hec1; HsHec1; Kinetochore-associated protein 2; Retinoblastoma-associated protein HEC
Application:
Immunofluorescence, Immunoprecipitation, Western Blot
Buffer:
PBS
translate.label.attr.clone:
Hec1 (9G3)
Clonality:
Recombinant Monoclonal
Formulation:
PBS only.
Host:
Mouse
Immunogen:
The original antibody was generated in mice by immunization with a purified protein fragment encompassing amino acids 56-632 of the human Hec1 protein.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody specifically binds amino acids 200-215 in the N terminal globular domain of the human Hec1 protein, exterior to Spc24 at metaphase kinetochores. It binds in a region which resides within the well-ordered calponin homology domain of the protein. Hec 1 protein acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spi
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies