Anti-CCL2 [MC32 affinity matured]
Product Sizes
1 mg
AB03459-10-3-BT-1MG
About this Product
- SKU:
- AB03459-10-3-BT
- Additional Names:
- MC32#56; MCP-1; MCP1; HC11; MCAF; C-C motif chemokine 2; monocyte chemoattractant protein 1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; Monocyte secretory protein JE; Small-inducible cytokine A2
- Application:
- Block/Inhibit/Neutralise, ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- MC32 affinity matured
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was isolated from a human scFv phage display library generated from the peripheral blood of 20 healthy donors by panning the library against human CCL2. Later on the scFv antibody was converted to a human IgG1 version using the variable regions of the scFv antibody and human framework regions.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human CCL2, which is a small chemokine molecule that acts as a ligand for C-C chemokine receptor (CCR2). The binding with CCR2 triggers strong chemotactic response and mobilization of intracellular calcium ions. CCL2 tightly regulates cellular mechanics and recruits monocytes, memory T cells and dendritic cells to the sites of inflammation. It exhibits a chemotactic activity fo
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03459-10.3-BT
