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Antibodies

Anti-GITR [2D3]

Product Sizes
200 ug
Was £463.00 £440.00
AB03421-10-3-200UG
About this Product
SKU:
AB03421-10-3
Additional Names:
CD357; TNFRSF18; AITR; GITR; Tumor necrosis factor receptor superfamily member 18; Activation-inducible TNFR family receptor; Glucocorticoid-induced TNFR-related protein; 2D3-mHvKv
Application:
ELISA, Flow Cytometry
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
2D3
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original antibody was generated by immunizing 6-8 weeks old female BALB/c mice with his-tagged human GITR protein.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human, Non-human Primate
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds human and rhesus monkey GITR (TNFRSF18; CD357) and does not cross react with mouse GITR. This protein acts as a receptor for TNFSF18, which is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies