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Antibodies

Anti-Desmoglein-3 [F779]

Product Sizes
200 ug
Was £463.00 £440.00
AB03419-10-0-200UG
About this Product
SKU:
AB03419-10-0
Additional Names:
DSG3; PVA; CDHF6; Desmoglein 3; 130 kDa pemphigus vulgaris antigen; Cadherin family member 6
Application:
ELISA, Immunofluorescence
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
F779
Clonality:
Recombinant Monoclonal
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original antibody was generated from the peripheral blood of four patients with active untreated pemphigus vulgaris (PV) using heterohybridoma techniques.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds human desmoglein-3 between amino acids 1-161 and does not cross react with desmoglein-1. It is a component of intercellular desmosome junctions. It is involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Pemphigus vulgaris (PV) is a potentially lethal skin disease in which epidermal blisters occur as the result of the loss of c
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies