Anti-Jo-1 [5B5]
Product Sizes
200 ug
AB03409-23-0-200UG
About this Product
- SKU:
- AB03409-23-0
- Additional Names:
- histidyl tRNA synthetase; Histidine--tRNA ligase, cytoplasmic; HisRS
- Application:
- ELISA, Western Blot
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- 5B5
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Chicken scFv format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Rabbit
- Immunogen:
- The original antibody was generated by immunizing a barnevelder chicken with an antibody antigen cocktail comprising recombinant purified human antigens annexin XI, CENP-B, Topo, Jo-1, Ro60, Rpp38 and U1A in complete Freund's adjuvant. B cells that were harvested from the bone marrow and peripheral blood lymphocytes of immunized chickens was used to generate recombinant scFv phage display libraries. The specific clone was identified by panning the library against specific antigen.
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody is specific for Jo-1. Histidyl-tRNA synthetase is a member of the aminoacyl-tRNA synthetase family, it catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP). Jo-1 represents a key autoantibody target in the anti-synthetase syndrome that is marked by myositis as well as extra-muscular orga
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03409-23.0
