Anti-CXCR3 [V44D7]
Product Sizes
1 mg
£1962.00
AB03380-3-0-BT-1MG
About this Product
- SKU:
- AB03380-3-0-BT
- Additional Names:
- CD183; CXC-R3; CXCR-3; CKR-L2; IP-10 receptor; GPR9; C-X-C chemokine receptor type 3; G protein-coupled receptor 9; Interferon-inducible protein 10 receptor
- Application:
- Block/Inhibit/Neutralise, ELISA, Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- V44D7
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- The original antibody was generated by immunizing BALB/c mice with CXCR-3 expressing NSO cells. The humanized version of the antibody was created by grafting CDRs of the original murine antibody onto human framework regions.
- Isotype:
- IgG2b
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human CXCR3. This protein acts as a receptor for C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway. Isoform 2 human mediates the proliferation, survival and angiogenic activity of microvascular endothelial cells (HMVEC) through a cAMP-media
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03380-3.0-BT
