Anti-CD127 [1A11 H3L4]
Product Sizes
1 mg
AB03376-23-0-BT-1MG
About this Product
- SKU:
- AB03376-23-0-BT
- Additional Names:
- IL7R; IL-7RA; CDw127; Interleukin-7 receptor subunit alpha; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; GSK2618960
- Application:
- Block/Inhibit/Neutralise, ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- 1A11 H3L4
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS only.
- Host:
- Rabbit
- Immunogen:
- The original parental mouse antibody1A11 was generated by immunizing C57BL/6 mice with a synthetic peptide (300 ug) of myelin oligodendrocyte glycoprotein (MOG residues 35-55). This antibody is a humanized and affinity matured version of 1A11.
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds the alpha component of the human IL-7RA (CD127). This antibody also cross reacts with cynomolgus monkey and marmoset IL-7Ra. This protein acts as a receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). Binding of IL-7 to the IL-7R activates multiple signaling pathways including the activation of JAK kinases 1 and 3 leading to the phosphory
- Storage Conditions:
- 2-8[o]C
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03376-23.0-BT
