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Antibodies

Anti-EGFR [cet.Hum (Cetuximab - humanized; hC225)]

Product Sizes
200 ug
Was £463.00 £440.00
AB03275-2-0-200UG
About this Product
SKU:
AB03275-2-0
Additional Names:
ERBB1; ERBB; ErbB-1, Erb-B1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Application:
Block/Inhibit/Neutralise, ELISA, Flow Cytometry, Western Blot
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
cet.Hum (Cetuximab - humanized; hC225)
Clonality:
Recombinant Monoclonal
Extra Details:
This full-length chimeric mouse antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Mouse
Immunogen:
The original antibody was generated by grafting CDR loops of cetuximab on framework regions derived from type 3 (VH3 and VL3 kappa) human germline sequences to obtain recombinant VH and VL domains linked together with a flexible linker [(Gly4Ser)3] to form a scFv.
Isotype:
IgG2a
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody recognizes human EGFR. The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies