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Antibodies

Anti-CHD4 [RAB-C211 ]

Product Sizes
1 mg
AB03246-10-27-BS-1MG
About this Product
SKU:
AB03246-10-27-BS
Additional Names:
CHD-4; Mi2; Mi-2; chromodomain helicase DNA binding protein 4; Chromodomain-helicase-DNA-binding protein 4; chromatin ATP-dependent helicase domain; ATP-dependent helicase CHD4; Mi-2 autoantigen 218 kDa protein; Mi2-beta; CHD4-RAB-C211; CHD4-A001-1307; CHD4-P001
Application:
ELISA, Immunofluorescence
Buffer:
PBS
translate.label.attr.clone:
RAB-C211
Clonality:
Recombinant Monoclonal
Extra Details:
This reformatted human antibody was made using the variable domain sequences of the original Human Fab format for improved compatibility with existing reagents assays and techniques.
Formulation:
PBS only.
Host:
Human
Immunogen:
The original antibodywas isoltated from an optimised automated phage display library by panning against specific antigens.
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds human chromodomain-helicase-DNA-binding protein 4 (CHD4). It is a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in the gene that encodes this protein are associated with serous endometrial tumors.
Storage Conditions:
2-8[o]C
Type:
Antibody: Recombinant Antibodies