Anti-IL-13 [M1295]
Product Sizes
200 ug
AB03210-10-0-200UG
About this Product
- SKU:
- AB03210-10-0
- Additional Names:
- IL13; NC30; Interleukin-13; hC836; m836; H2L6; LC6HC2; HFAL62
- Application:
- Block/Inhibit/Neutralise, ELISA
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- M1295
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Human
- Immunogen:
- The original mouse antibody m836 was generated by immunizing BALB/c mice with a natural variant of human IL-13 known as R130Q. The humanized version H2L6 was generated by grafting CDRs of mouse antibody onto selected human heavy chain and light chain frameworks and finally site-directed mutagenesis of two methionine in the CDRs of heavy chain with binding affinity optimization resulted in the generated of M1295.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human interleukin-13 at the surface of helices A and D close to N- and C-termini of the IL-13 polypeptide chain. IL-13 is a cytokine secreted by T helper type 2 (Th2) cells, CD4 cells, natural killer T cell, mast cells, basophils, eosinophils and nuocytes. It inhibits the production of inflammatory cytokines (IL-1, IL-6, TNF, IL-8) by LPS-stimulated monocytes. It synergizes wit
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03210-10.0
