Anti-Glypican 3 [7H1]
Product Sizes
1 mg
AB03200-10-3-BT-1MG
About this Product
- SKU:
- AB03200-10-3-BT
- Additional Names:
- GPC3; Glypican-3; GPC-3; GTR2-2; MXR7; OCI5; DGSX; Intestinal protein OCI-5
- Application:
- ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 7H1
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was generated by immunizing BALB/c mice with a recombinant human GPC3 extracellular domain (ECD, amino acids of 1-547) fused to a C-terminal Flag (RADYKDDDDK).
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Mouse, Non-human Primate, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds an epitope between amino acids 25 to 137 of the human glypican 3 (GPC3). This antibody cross reacts with cynomolgus monkey, rat and mouse GPC3. Glypican-3 is an oncofetal antigen that belongs to the glypican family of glycosyl-phosphatidylinositol-anchored heparin sulfate proteoglycans. It negatively regulates the hedgehog signaling pathway and positively regulates the canonica
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03200-10.3-BT
