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Antibodies

Anti-MSH2 [1B11-14-16]

Product Sizes
200 ug
Was £463.00 £440.00
AB03191-10-0-200UG
About this Product
SKU:
AB03191-10-0
Additional Names:
hMSH2; DNA mismatch repair protein Msh2; MutS protein homolog 2; CGMCC NO.17405; G219-1129
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
1B11-14-16
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original antibody was generated by immunizing BALB/c mice with human MSH2 protein peptide (KLH-NSFVNEIISRIKVTT-Cys) conjugated with KLH in equal volume of Freund's complete adjuvant.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds an epitope on the human DNA mismatch protein MSH2 between amino acids 919-934 (NSFVNEIISRIKVTT). MSH2 forms a heterodimer with MSH6 to make the human MutSA Alpha mismatch repair complex. The DNA mismatch repair system (MMR) is composed of enzyme molecules that specifically repair DNA base mismatches. MSH2 is involved in many different forms of DNA repair, including transcriptio
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies