Anti-p16 [30859-S17]
Product Sizes
200 ug
AB03149-23-0-200UG
About this Product
- SKU:
- AB03149-23-0
- Additional Names:
- CDKN2A; CDKN2; CDK4I; MTS-1; p16-INK4a; p16-INK4; p16INK4A; cyclin-dependent kinase inhibitor 2A; Cyclin-dependent kinase 4 inhibitor; Multiple tumor suppressor 1; E6H4
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- 30859-S17
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Rabbit
- Immunogen:
- The original antibody was generated by immunizing BALB/c mice with recombinant p16 antigen protein.
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human p16, which is located in the nucleus and cytoplasm. It acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03149-23.0
