Anti-TIGIT [4A5]

Product Sizes

1 mg

AB03137-10-0-BT-1MG

About this Product

SKU:: AB03137-10-0-BT
Additional Names:: VSTM3; VSIG9; WUCAM; T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain-containing protein 3
Application:: Block/Inhibit/Neutralise, ELISA, Flow Cytometry
Buffer:: PBS
translate.label.attr.clone:: 4A5
Clonality:: Recombinant Monoclonal
Extra Details:: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Formulation:: PBS only.
Host:: Human
Immunogen:: The original antibody was generated by immunizing 9 week old BALB/c mice with recombinant human TIGIT extracellular region Fc fusion protein in complete Freund's adjuvant.
Isotype:: IgG1
Purification:: Purified
Reactivities:: Human
Shipping Conditions:: Blue Ice
Specificity:: This antibody binds the extracellular domain of the human TIGIT (T cell immunoreceptor with Ig and ITIM domains). TIGIT is a type I transmembrane protein that is a member of the CD28 family within the Ig superfamily of proteins. It is an immune receptor present on some T cells and natural killer cells (NK). It binds the poliovirus receptor (PVR) with high affinity which causes increased secretion
Storage Conditions:: 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:: Absolute Antibody
Type:: Antibody: Recombinant Antibodies

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