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Antibodies

Anti-BCMA [13A4]

Product Sizes
200 ug
Was £463.00 £440.00
AB03125-10-3-200UG
About this Product
SKU:
AB03125-10-3
Additional Names:
CD269; BCM; TNFRSF17; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein
Application:
ELISA, Flow Cytometry
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
13A4
Clonality:
Recombinant Monoclonal
Extra Details:
This reformatted human antibody was made using the variable domain sequences of the original Human Fab format for improved compatibility with existing reagents assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original antibody was isolated from a generic Fab antibody library by panning against biotinylated ectodomain of BCMA.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds human BCMA. It acts as a receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. BCMA expression is highest on terminally differentiated B cells. BCMA is involved in mediating the survival of plasma cells for maintaining long-term humoral immunity. It also activates NF-kappa-B and JNK. The expression of BCMA has been linked to a number of cancers, autoimmune disorders, and infectiou
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies