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Antibodies

Anti-CD47 [h4C1]

Product Sizes
200 ug
Was £463.00 £440.00
AB03104-10-0-200UG
About this Product
SKU:
AB03104-10-0
Additional Names:
IAP; MER6; OV-3; Leukocyte surface antigen CD47; Antigenic surface determinant protein OA3; Integrin-associated protein; Protein MER6; ovarian cancer marker; 4C1
Application:
Block/Inhibit/Neutralise, ELISA, Flow Cytometry
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
h4C1
Clonality:
Recombinant Monoclonal
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original mouse antibody was generated by immunizing BALB/c mice with human CD47-ecto recombinant protein emulsified with complete Freund's adjuvant. Later on the original mouse antibody was used to generate the humanized version of the antibody using sequence homology and computational prediction.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds the FG loop of the human CD47, which interacts with SIRPA Alpha and several other known CD47/SIRPA Alpha-blocking mAb. CD47 is broadly distributed on normal adult tissues, as well as ovarian tumors, and is especially abundant in some epithelia and the brain. IAP or integrin assocaited protein has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platel
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies