Anti-Myelin basic protein [B5V6]
Product Sizes
1 mg
AB03095-10-0-BT-1MG
About this Product
- SKU:
- AB03095-10-0-BT
- Additional Names:
- MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein
- Application:
- ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- B5V6
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This full-length reformatted human antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was isolated from a phage display library of single-chain variable fragments (scFvs), which was constructed from blood lymphocytes of patienst with MS as a potential source of representative MS autoantibodies.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Bovine, Virus
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds bovine myelin binding protein (MBP) both in its native and denatured form in the region between amino acids 130-156. The MBP isoforms 4 and 14 along with PLP are most abundant protein components of the myelin membrane in the CNS. The smaller isoforms are believed to have an important role in remyelination of denuded axons in multiple sclerosis.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03095-10.0-BT
