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Antibodies

Anti-Myelin basic protein [845D3]

Product Sizes
200 ug
Was £463.00 £440.00
AB03092-10-3-200UG
About this Product
SKU:
AB03092-10-3
Additional Names:
MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein; 84-5D3
Application:
ELISA, Radioimmunoassay
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
845D3
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original antibody was generated by hyperimmunization of BALB/c mice with human MBP peptide comprising amino acids from 80-89.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Bovine, Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds human myelin basic protein (MBP), amino acid residues 80-89 (QDENPVVHF). This antibody also cross reacts with bovine MBP comprising amino acids 78-88. The MBP isoforms 4 and 14 along with PLP are most abundant protein components of the myelin membrane in the CNS. The smaller isoforms are believed to have an important role in remyelination of denuded axons in multiple sclerosis.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies