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Antibodies

Anti-Arginase 1 [mAb5]

Product Sizes
200 ug
Was £463.00 £440.00
AB03081-23-0-200UG
About this Product
SKU:
AB03081-23-0
Additional Names:
ARG1; Arginase-1; Liver-type arginase; Type I arginase
Application:
Block/Inhibit/Neutralise, Electron Microscopy
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
mAb5
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Rabbit
Immunogen:
The antibody was generated by immunizing mice with recombinant arginase 1.
Isotype:
IgG
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
The antibody binds arginase 1. The binding of the antibody does not sterically block the Arginase 1 active site, but it interacts with an amino acid (Arg21) important to substrate binding by arginase 1, thereby inhibiting enzyme activity. Arginase is a manganese-containing enzyme that catalyzes the hydrolysis of L-arginine to L-ornithine and urea, and modulates T-cell-mediated immune response.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies