Anti-Arginase 1 [mAb5]
Product Sizes
1 mg
AB03081-23-0-BT-1MG
About this Product
- SKU:
- AB03081-23-0-BT
- Additional Names:
- ARG1; Arginase-1; Liver-type arginase; Type I arginase
- Application:
- Block/Inhibit/Neutralise, Electron Microscopy
- Buffer:
- PBS
- translate.label.attr.clone:
- mAb5
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS only.
- Host:
- Rabbit
- Immunogen:
- The antibody was generated by immunizing mice with recombinant arginase 1.
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody binds arginase 1. The binding of the antibody does not sterically block the Arginase 1 active site, but it interacts with an amino acid (Arg21) important to substrate binding by arginase 1, thereby inhibiting enzyme activity. Arginase is a manganese-containing enzyme that catalyzes the hydrolysis of L-arginine to L-ornithine and urea, and modulates T-cell-mediated immune response.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03081-23.0-BT
