Anti-VEGFR2 [IMC-1121B (Ramucirumab)]
Product Sizes
1 mg
AB03058-23-0-BT-1MG
About this Product
- SKU:
- AB03058-23-0-BT
- Additional Names:
- Vascular endothelial growth factor receptor 2; kinase insert domain-containing receptor; KDR; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1; CD309; VEGFR-2; Cyramza; LY3009806; 947687-13-0
- Application:
- Cell-based/Functional Assay, Crystallography, Flow Cytometry, Immunohistochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- IMC-1121B (Ramucirumab)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rabbit antibody was made using the variable domain sequences of the original Human Fab format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS only.
- Host:
- Rabbit
- Immunogen:
- The original antibody was generated by using phage display technology. A new library comprising the single VH paired with the variable light chain (VL) repertoire obtained from the original naive human library was constructed, followed by phage display-based selection.
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody specifically recognizes VEGFR-2 and it binds to domain 3 of VEGFR2. VEGFR2 is a tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. It plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cel
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03058-23.0-BT
