Anti-Integrin alpha.sub.v.beta.sub.3 [LM609]
Product Sizes
1 mg
AB03055-10-3-BT-1MG
About this Product
- SKU:
- AB03055-10-3-BT
- Additional Names:
- A AlphavB Beta3; A AlphaVB Beta3 integrin; alphav beta3 integrin; Vitronectin receptor; Vitronectin receptor subunit alpha; CD51; MED-523; Vitaxin; Etaracizumab; Abegrin
- Application:
- Block/Inhibit/Neutralise, Crystallography, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
- Buffer:
- PBS
- translate.label.attr.clone:
- LM609
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was generated by immunizing BALB/c mice with purified cell adhesion receptor.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- The antibody specifically recognizes A AlphaVB Beta3 integrin. In particular, it recognizes an epitope on the A AlphaVB Beta3 integrin headpiece apex at the interface between the B Beta-propeller and B BetaI domains, sterically hindering access of large ligands to the RGD binding pocket.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03055-10.3-BT
