Anti-FOLR1 [Farletuzumab (MORAb-003; M3)]
Product Sizes
200 ug
AB03043-10-3-200UG
About this Product
- SKU:
- AB03043-10-3
- Additional Names:
- FRA; FrA Alpha; Fr-A Alpha; FBP; LK26; Folate receptor 1; Folate receptor alpha; FR-alpha; Adult folate-binding protein; Ovarian tumor-associated antigen MOv18; KB cells FBP; Folate receptor adult; MOv18
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA, Immunohistochemistry
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- Farletuzumab (MORAb-003; M3)
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Human
- Immunogen:
- The original parental mouse antibody was generated by immunizing (BALB/c X C57BL/6) F1 mice by intraperitoneal injection containing cultured LU-75(c) choriocarcinoma cells to produce hybridomas that generated the antibody LK26. Later on the Farletuzumab was generated by CDR grafting technique by taking CDRs of mouse parental clone LK26 and grafting them on human framework regions.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human folate receptor alpha (FOLR1). FOLR1 binds folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells by receptor mediated endocytosis. It is required for normal embryonic development and normal cell proliferation. The human folate receptor-alpha (FOLR1) is overexpressed in ovarian cancer but l
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03043-10.3
