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Antibodies

Anti-EGFRvIII [806]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB03036-3-3-BT-1MG
About this Product
SKU:
AB03036-3-3-BT
Additional Names:
de2-7 EGFR; EGF receptor; delta2-7 epidermal growth factor receptor; Epidermal Growth Factor Receptor variant III
Application:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Buffer:
PBS
translate.label.attr.clone:
806
Clonality:
Recombinant Monoclonal
Formulation:
PBS only.
Host:
Mouse
Immunogen:
The original antibody was generated by immunization of mice with NR6 mouse fibroblasts expressing the truncated de2-7 EGFR.
Isotype:
IgG2b
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for the human delta2-7 epidermal growth factor receptor (de2-7 EGFR or EGFRvIII) which is a truncated version of the EGFR commonly expressed in glioma. This antibody does not bind wild type EGF receptor. Studies have shown that it binds a cryptic epitope on the EGFR in the region between amino acids 287-302, and it is suggested that breaking the disulfide bond preceding t
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies