Anti-BRAF V600E protein [600E-7]
Product Sizes
1 mg
AB03009-10-0-BT-1MG
About this Product
- SKU:
- AB03009-10-0-BT
- Additional Names:
- RAFB1; BRAF1; p94; BRAF V600E kinase; Serine/threonine-protein kinase B-raf; Proto-oncogene B-Raf; v-Raf murine sarcoma viral oncogene homolog B1
- Application:
- ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- 600E-7
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was generated by immunizing mice with double repeat recombinant BRAF V600E protein 'GDFGLATEKSRW' and BRAF V600 protein 'GDFGLATVKSRW' in equal amount of complete Freund's adjuvant.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for the V600E mutation of the BRAF protein kinase. BRAF V600E mutation can promote the methylation of the thyrotropin receptor (TSHR) gene promoter, resulting in silencing of TSHR or a significant decrease in expression, and feedback increase of thyrotropin (TSH), which promotes the growth of tumor cells. BRAF V600E gene mutation and telomerase reverse transcriptase (TERT
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab03009-10.0-BT
