Anti-TRKB [C2]

Product Sizes

1 mg

£1962.00

AB03000-10-3-BT-1MG

About this Product

SKU:: AB03000-10-3-BT
Additional Names:: NTRK2; Trk-B; GP145-TrkB; TrkB tyrosine kinase; Tropomyosin-related kinase; BDNF/NT-3 growth factors receptor; Neurotrophic tyrosine kinase receptor type 2; Tropomyosin receptor kinase B; tyrosine receptor kinase B
Application:: Activate/Stimulate, Block/Inhibit/Neutralise, ELISA
Buffer:: PBS
translate.label.attr.clone:: C2
Clonality:: Recombinant Monoclonal
Formulation:: PBS only.
Host:: Human
Immunogen:: The original antibody was generated by grafting of the murine antibody 38B8 CDRs onto human framework regions. The parental murine antibody 38B8 was generated by immunizing mice with human TRKB.
Isotype:: IgG1
Purification:: Purified
Reactivities:: Human, Mouse, Rat
Shipping Conditions:: Blue Ice
Specificity:: This antibody binds human TRKB and also cross reacts with mouse and rat TRKB. TRKB is a membrane bound receptor for brain-derived neurotrophic factor (BDNF). Upon neurotrophin binding it phosphorylates itself and members of the MAPK pathway. Signaling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders.
Storage Conditions:: 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:: Absolute Antibody
Type:: Antibody: Recombinant Antibodies

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