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Antibodies

Anti-Norovirus capsid protein VP1 [A1227]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB02975-23-0-BT-1MG
About this Product
SKU:
AB02975-23-0-BT
Additional Names:
VP1; CP; p59; soluble capsid protein; Protein 30k; p30; Norwalk virus
Application:
ELISA
Buffer:
PBS
translate.label.attr.clone:
A1227
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.
Formulation:
PBS only.
Host:
Rabbit
Immunogen:
The original antibody was isolated from an anti-NoV GII.4c IgG serum antibody repertoire generated from three donors that experienced a significant increase in GII.4 titer after immunization with the bivalent GII.4c + GI.1 VLP vaccine.
Isotype:
IgG
Purification:
Purified
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Specificity:
This antibody shows broadly binding but no blocking activity toward multiple GI and GII strains such as GI.I, GII.2, and GII.17. This antibody recognizes a highly conserved epitope located at an occluded site on the norovirus capsid, at the interface between the P domain and shell domain of the Norovirus, which explain its high level of cross-reactivity. Norovirus (NoVs) is one of the main pathoge
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies