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Antibodies

Anti-Norovirus capsid protein VP1 [A1227]

Product Sizes
200 ug
Was £463.00 £440.00
AB02975-1-1-200UG
About this Product
SKU:
AB02975-1-1
Additional Names:
VP1; CP; p59; soluble capsid protein; Protein 30k; p30; Norwalk virus
Application:
ELISA
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
A1227
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Mouse
Immunogen:
The original antibody was isolated from an anti-NoV GII.4c IgG serum antibody repertoire generated from three donors that experienced a significant increase in GII.4 titer after immunization with the bivalent GII.4c + GI.1 VLP vaccine.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Specificity:
This antibody shows broadly binding but no blocking activity toward multiple GI and GII strains such as GI.I, GII.2, and GII.17. This antibody recognizes a highly conserved epitope located at an occluded site on the norovirus capsid, at the interface between the P domain and shell domain of the Norovirus, which explain its high level of cross-reactivity. Norovirus (NoVs) is one of the main pathoge
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies