Anti-Norovirus GII.4 P domain [A1431]

Product Sizes

1 mg

AB02974-16-0-BS-1MG

About this Product

SKU:: AB02974-16-0-BS
Additional Names:: VP1; NoV; HuNoV; NoV VP1; capsid protein VP1; major capsid protein; Norovirus GII.4; Norwalk virus
Application:: Block/Inhibit/Neutralise, ELISA
Buffer:: PBS
translate.label.attr.clone:: A1431
Clonality:: Recombinant Monoclonal
Extra Details:: This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:: PBS only.
Host:: Human
Immunogen:: The original antibody was isolated from an anti-NoV GII.4c IgG serum antibody repertoire generated from three donors that experienced a significant increase in GII.4 titer after immunization with the bivalent GII.4c + GI.1 VLP vaccine.
Isotype:: IgA1
Purification:: Purified
Reactivities:: Virus
Shipping Conditions:: Blue Ice
Specificity:: This antibody recognizes conserved residues distal to the HBGA binding pocket but accessible on the assembled VLP. It binds each P domain monomer at a cleft between the P1 and P2 subdomains. Norovirus (NoVs) is one of the main pathogens causing sporadic cases and large outbreaks of acute gastroenteritis, and norovirus can infect people of all ages.
Storage Conditions:: 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:: Absolute Antibody
Type:: Antibody: Recombinant Antibodies

Basket