Anti-PCSK9 [3D2]
Product Sizes
1 mg
AB02937-10-0-BT-1MG
About this Product
- SKU:
- AB02937-10-0-BT
- Additional Names:
- NARC1; NARC-1; PC9; Proprotein convertase subtilisin/kexin type; Neural apoptosis-regulated convertase 1; Proprotein convertase 9; Subtilisin/kexin-like protease PC9
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA
- Buffer:
- PBS
- translate.label.attr.clone:
- 3D2
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was isolated from an scFv phage display library generated from blood, bone marrow, and cord blood samples from healthy donors by panning against recombinant PCSK9.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds PCSK9 and blocks the PCSK9-LDLR interaction in a dose-dependent manner with an IC50 of 2.25+/-1.23 nM (PMID: 33416098). Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease enzyme encoded by the PCSK9 gene in humans and it plays a role in regulation of circulating cholesterol. It is associated with autosomal dominant hypercholesterolemia, a state of elevat
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02937-10.0-BT
