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Antibodies

Anti-Frizzled [1C11-B9-H9-G9-D9]

Product Sizes
1 mg
AB02919-23-0-BT-1MG
About this Product
SKU:
AB02919-23-0-BT
Additional Names:
Frizzled protein; fz; Frizzled-1; dFz1
Application:
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Buffer:
PBS
translate.label.attr.clone:
1C11-B9-H9-G9-D9
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Rabbit
Immunogen:
The mouse version of this antibody was generated by immunizing a mouse with amino acids 1-252 of Drosophila Frizzled.
Isotype:
IgG
Purification:
Purified
Reactivities:
Insect/Arthropod
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for drosophila frizzled. It is specific for amino acids 1-252. Frizzled is a receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies