Anti-CD49E [SAM1]

Product Sizes

1 mg

AB02881-10-0-BT-1MG

About this Product

SKU:: AB02881-10-0-BT
Additional Names:: SAM-1; Integrin Alpha 5
Application:: Cell-based/Functional Assay, Flow Cytometry, Immunofluorescence, Immunohistochemistry
Buffer:: PBS
translate.label.attr.clone:: SAM1
Clonality:: Recombinant Monoclonal
Extra Details:: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.
Formulation:: PBS only.
Host:: Human
Immunogen:: The mouse version of this antibody was raised by immunizing a BALB/c mouse with U 937 cells.
Isotype:: IgG1
Purification:: Purified
Reactivities:: Human
Shipping Conditions:: Blue Ice
Specificity:: This antibody is specific for human CD49E. CD49E is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. CD49E binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.
Storage Conditions:: 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:: Absolute Antibody
Type:: Antibody: Recombinant Antibodies

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