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Antibodies

Anti-CD18 [YFC51.1]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB02841-10-3-BT-1MG
About this Product
SKU:
AB02841-10-3-BT
Additional Names:
ITGB2; MFI7; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150.95 subunit beta; Complement receptor C3 subunit beta; B Beta2-subunit of leukocyte integrins
Application:
Block/Inhibit/Neutralise, ELISA
Buffer:
PBS
translate.label.attr.clone:
YFC51.1
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Rat IgG2b format for improved compatibility with existing reagents assays and techniques.
Formulation:
PBS only.
Host:
Human
Immunogen:
The original antibody was generated by immunizing DA rats with human neutrophils.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds human CD18 and recognizes amino acid residues between 122 and 344, more particularly amino acids from two regions 123-163 and 302-344 of the human CD18 molecule (PMID: 10779511). Binding of CD18 and CD11 results in the formation of Lymphocyte Functions Associated Antigen 1 (LFA-1), a protein found on B cells, all T cells, macrophages, neutrophils and NK cells. LFA-1 is involved
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies