Anti-VEGF-D [VD1 (4A5)]
Product Sizes
1 mg
AB02839-1-1-BT-1MG
About this Product
- SKU:
- AB02839-1-1-BT
- Additional Names:
- VEGFD; FIGF; Vascular endothelial growth factor D; c-Fos-induced growth factor
- Application:
- Block/Inhibit/Neutralise, ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- VD1 (4A5)
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- The original antibody was generated by immunizing female BALB/c mice with truncated portion of human VEGF-D from residue 93 to 201, which had FLAG-tag at its N-terminus.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human VEGF-D and block the binding of VEGF-D to both VEGFR-2 and VEGFR-3. Peptide-based mapping and site-directed mutagenesis suggested that binding epitope of this antibody includes the five residues 147NEESL151of the VEGF-D (PMID: 21315726). VEGF-D signaling through the VEGFR-3 receptor has been shown to be the primary source of lymphangiogenic activation and has also been no
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02839-1.1-BT
