Anti-CD146 [ABX-MA1 (3.19.1)]
Product Sizes
200 ug
AB02820-10-3-200UG
About this Product
- SKU:
- AB02820-10-3
- Additional Names:
- MCAM; MUC18; Mel-CAM; cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; melanoma cell adhesion molecule; melanoma-associated antigen A32; melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; c3.19.1
- Application:
- Cell-based/Functional Assay, ELISA, Flow Cytometry, Western Blot
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- ABX-MA1 (3.19.1)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This reformatted human antibody was made using the variable domain sequences of the original Human IgG2 format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Human
- Immunogen:
- The original antibody was generated by immunizing XenoMouse® mice with SK-MEL-28 cells admixed 1:1 v/v with Complete Freund's Adjuvant (CFA), followed by four injections with 5 ug soluble MUC18-human IgG2 Fc fusion protein admixed 1:1 v/v with Incomplete Freund's Adjuvant (IFA) and then a final boost of 10 ug soluble MUC18-human IgG2 Fc fusion protein without adjuvant.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds human CD146 (MCAM/MUC18). CD146 is a cell-surface glycoprotein composed of a signal peptide, five immunoglobulin-like domains, a transmembrane region, and a short cytoplasmic tail . Its expression is associated with tumor progression and the development of metastatic potential.
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02820-10.3
