Anti-Glycoprotein E2 [HC84.26.5D (HC26AM)]
Product Sizes
1 mg
AB02817-10-3-BT-1MG
About this Product
- SKU:
- AB02817-10-3-BT
- Additional Names:
- NS1; gp68; gp70; HCV glycoprotein E2; Genome polyprotein; Envelope glycoprotein E2; E2 glycoprotein; H77; HC84.26
- Application:
- Block/Inhibit/Neutralise, ELISA, Immunoprecipitation
- Buffer:
- PBS
- translate.label.attr.clone:
- HC84.26.5D (HC26AM)
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original antibody was isolated from a yeast display library constructed from peripheral B cells from a donor with asymptomatic chronic HCV genotype 2b infection. The donor's serum contained a high antibody binding titer (>1:10,000) to E2 and similarly high neutralizing titers against genotype 2a JFH1 HCVcc and 1a H77C HCVpp. Affinity maturation of the original antibody was done using a yeast display approach to isolate the clones that have improved binding and neutralization activities against HCV isolates.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Virus
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody recognizes a conformation dependent antigenic epitope on the E2 glycoprotein. This antibody specifically binds the antigenic domain D of the virus comprising amino acids 441, 442, 446 and 616 (PMID: 22511875).
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02817-10.3-BT
