Anti-Citrullinated collagen type II [ACC1]
Product Sizes
1 mg
AB02800-23-0-BT-1MG
About this Product
- SKU:
- AB02800-23-0-BT
- Additional Names:
- ACPA; CII; Col II; COL2A1; citrullinated CII; citrullinated Col II; Col C II; citrullinated proteins; antibodies against citrullinated proteins; Collagen alpha-1(II) chain; Alpha-1 type II collagen
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- ACC1
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques.
- Formulation:
- PBS only.
- Host:
- Rabbit
- Immunogen:
- The original antibody was generated by immunizing a Cia5 congenic B10.RIII mouse with bovine collagen type II (CII).
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Bovine, Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds triple helical citrullinated form of C1 epitope (amino acids 359 - 369 : ARGLTGRPGDA) of collagen type II. The ACC1 antibody cross reacts with denatured CII as well as the denatured triple helical C1 epitope. C1 peptide contains two arginine which are post translationally converted to citrulline. ACC1 was found to recognize the second citrulline at position 365 (PMID: 19204106)
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02800-23.0-BT
