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Antibodies

Anti-Citrullinated collagen type II [ACC1]

Product Sizes
200 ug
Was £463.00 £440.00
AB02800-2-3-200UG
About this Product
SKU:
AB02800-2-3
Additional Names:
ACPA; CII; Col II; COL2A1; citrullinated CII; citrullinated Col II; Col C II; citrullinated proteins; antibodies against citrullinated proteins; Collagen alpha-1(II) chain; Alpha-1 type II collagen
Application:
ELISA, Immunohistochemistry
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
ACC1
Clonality:
Recombinant Monoclonal
Formulation:
PBS with 0.02% Proclin 300.
Host:
Mouse
Immunogen:
The original antibody was generated by immunizing a Cia5 congenic B10.RIII mouse with bovine collagen type II (CII).
Isotype:
IgG2a
Purification:
Purified
Reactivities:
Bovine, Human, Mouse
Shipping Conditions:
Blue Ice
Specificity:
This antibody binds triple helical citrullinated form of C1 epitope (amino acids 359 - 369 : ARGLTGRPGDA) of collagen type II. The ACC1 antibody cross reacts with denatured CII as well as the denatured triple helical C1 epitope. C1 peptide contains two arginine which are post translationally converted to citrulline. ACC1 was found to recognize the second citrulline at position 365 (PMID: 19204106)
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies