Anti-Glycoprotein E2 [HC-1AM]
Product Sizes
200 ug
AB02799-10-3-200UG
About this Product
- SKU:
- AB02799-10-3
- Additional Names:
- E1E2 complex; NS1; gp68; gp70; HCV glycoprotein E2; Genome polyprotein; Envelope glycoprotein E2; E2 glycoprotein; Glycoprotein E2; HC1AM; HC-1
- Application:
- Block/Inhibit/Neutralise, ELISA, Flow Cytometry
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- HC-1AM
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Human
- Immunogen:
- The original IgG2 HC-1 antibody was isolated from peripheral blood B cells of an individual with chronic HCV genotype 1a infection who had a high serum antibody binding titer to E2 and high neutralizing activity (>1:10,000 titer) against genotype 1a HCVpp. The B cells were activated by Epstein-Barr virus and used to produce human hybridomas. The affinity-matured version of HC-1 (called HC-1AM) was created by constructing a library of yeast-displayed HC-1 single chain Fv (scFv) mutants and selecting the relevant high affinity binders.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Virus
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody recognizes a conformation dependent epitope (domain B) on the E2 glycoprotein of hepatitis C virus.
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02799-10.3
