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Antibodies

Anti-Glycoprotein E2 [HC-11]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB02798-10-0-BT-1MG
About this Product
SKU:
AB02798-10-0-BT
Additional Names:
E1E2 complex; NS1; gp68; gp70; HCV glycoprotein E2; Genome polyprotein; Envelope glycoprotein E2; E2 glycoprotein; Glycoprotein E2; HC11
Application:
Block/Inhibit/Neutralise, ELISA, Flow Cytometry, Immunofluorescence, Immunoprecipitation
Buffer:
PBS
translate.label.attr.clone:
HC-11
Clonality:
Recombinant Monoclonal
Formulation:
PBS only.
Host:
Human
Immunogen:
The original antibody was isolated from peripheral blood B cells of an individual with chronic HCV genotype 1a infection who had a high serum antibody binding titer to E2 and high neutralizing activity (>1:10,000 titer) against genotype 1a HCVpp. The B cells were activated by Epstein-Barr virus and used to produce human hybridomas.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Virus
Shipping Conditions:
Blue Ice
Specificity:
This antibody recognizes a conformation dependent epitope (domain B) on the E2 glycoprotein of hepatitis C virus. This antibody was reported to bind 2 regions of the E2 glycoprotein from amino acid residues 425 to 443 and aa 529 to 535 (PMID: 21813602).
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies