Anti-Desmoglein 3 [AK23]
Product Sizes
200 ug
AB02730-1-1-200UG
About this Product
- SKU:
- AB02730-1-1
- Additional Names:
- DSG3; PVA; CDHF6; Desmoglein-3; 130 kDa pemphigus vulgaris antigen; Cadherin family member 6
- Application:
- ELISA, Immunofluorescence, Immunoprecipitation
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- AK23
- Clonality:
- Recombinant Monoclonal
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Mouse
- Immunogen:
- The original antibody was generated by immunizing Dsg3 knockout mice with recombinant mouse Dsg3-His in complete Freund's adjuvant subcutaneously.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody binds mouse Dsg3 and also shows reactivity for human Dsg3. It does not show any affinity towards Dsg1. AK23 recognizes a calcium-dependent conformational epitope on Dsg3, which consisted of the V3, K7, P8, and D59 Dsg3-specific residues that formed the adhesive interface between juxtaposed Dsg.
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02730-1.1
