Anti-Notch3 [7G7-B10-H3]
Product Sizes
200 ug
AB02629-10-3-200UG
About this Product
- SKU:
- AB02629-10-3
- Additional Names:
- Notch 3 extracellular truncation; Notch 3 intracellular domain; Neurogenic locus notch homolog protein 3
- Application:
- Cell-based/Functional Assay, Western Blot
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- 7G7-B10-H3
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Human
- Immunogen:
- The original mouse version of this antibody was raised by immunizing a mouse with human notch 3.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for amino acids 807-884 of human notch3. Notch 3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the imple
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02629-10.3
