Anti-p130/CAS [8G4]
Product Sizes
1 mg
AB02626-10-3-BT-1MG
About this Product
- SKU:
- AB02626-10-3-BT
- Additional Names:
- Breast cancer anti-estrogen resistance protein 1; Bcar1; CRK-associated substrate; p130cas
- Application:
- Immunofluorescence, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 8G4
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original mouse version of this antibody was raised by immunizing a mosue with a GST fusion protein corresponding to residues 576-796 of rat p130 Cas.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for p130/CAS amino acids 576 to 796 and recognizes rat, mouse and human homologs. P130cas is a docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion (By similarity). Implicated in induction of cell migration and cell branching (By similarity). Involved in the BCAR3-mediated inhibition of TGFB signaling (By sim
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02626-10.3-BT
