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Antibodies

Anti-p130/CAS [8G4]

Product Sizes
200 ug
Was £463.00 £440.00
AB02626-10-0-200UG
About this Product
SKU:
AB02626-10-0
Additional Names:
Breast cancer anti-estrogen resistance protein 1; Bcar1; CRK-associated substrate; p130cas
Application:
Immunofluorescence, Western Blot
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
8G4
Clonality:
Recombinant Monoclonal
Extra Details:
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS with 0.02% Proclin 300.
Host:
Human
Immunogen:
The original mouse version of this antibody was raised by immunizing a mosue with a GST fusion protein corresponding to residues 576-796 of rat p130 Cas.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for p130/CAS amino acids 576 to 796 and recognizes rat, mouse and human homologs. P130cas is a docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion (By similarity). Implicated in induction of cell migration and cell branching (By similarity). Involved in the BCAR3-mediated inhibition of TGFB signaling (By sim
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies