Anti-CXCR4 [427aB1]
Product Sizes
1 mg
AB02487-1-1-BT-1MG
About this Product
- SKU:
- AB02487-1-1-BT
- Additional Names:
- C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; FB22; Fusin; Fusin; LCR1; Leukocyte-derived seven transmembrane domain receptor; LESTR; Lipopolysaccharide-associated protein 3; LAP-3; LPS-associated protein 3; NPYRL; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD184
- Application:
- Cell-based/Functional Assay, ELISA, Flow Cytometry, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 427aB1
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- The original mouse antibody was raised by immunizing balb/c mice with recombinant NIH3T3-CXCR4 cells and peptides corresponding to CXCR4 extracellular N-term and loops.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for human CXCR4. It binds to both the monomers and homodimers. CXCR4 is a receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade. Plays a role in regulation of cell migration, e.g. during wound healing.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02487-1.1-BT
