Anti-MSCP [LC007]
Product Sizes
1 mg
AB02486-10-3-BT-1MG
About this Product
- SKU:
- AB02486-10-3-BT
- Additional Names:
- Mitoferrin-1; SLC25A37; Mitochondrial iron transporter 1; Mitochondrial solute carrier protein; Solute carrier family 25 member 37
- Application:
- Cell-based/Functional Assay, Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- LC007
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Human
- Immunogen:
- The original mouse antibody was raised by immunizing Balb/c mice with a synthetic peptide corresponding to aa 2177-2221 of the human MCSP sequence coupled to KLH.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody is specific for repeat 14 of MSCP or for an epitope that is only reconstituted when repeat 14 is present. It also binds to cynomolgus MSCP. MSCP is a mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe2+, is then probably
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02486-10.3-BT
