Anti-CCR2 [AbAb-CCR2]
Product Sizes
1 mg
AB02444-23-BT-1MG
About this Product
- SKU:
- AB02444-23-BT
- Additional Names:
- CD192; C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; Monocyte chemoattractant protein 1 receptor; MCP-1-R; JE/FIC receptor; CMKBR2
- Application:
- Block/Inhibit/Neutralise, Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- AbAb-CCR2
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a reformatted mouse IgG2a Fc Silent™ antibody, based on the original mouse IgG2b format, created for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- The original antibody was generated by immunizing rats with CHO cells stably transfected with mouse CCR2.
- Isotype:
- IgG2a
- Purification:
- Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody specifically binds mouse CCR2 and does not cross react with mouse CCR5 or human CCR2 and CCR5. CCR2 is a key functional receptor for CCL2 but can also bind CCL7 and CCL12 chemokines. Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration. It regulates the expression of T-cell inflammatory cytokines and T-cell differentiation, promoting the differentiatio
- Storage Conditions:
- 2-8[o]C
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02444-23-BT