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Antibodies

Anti-Tau [MN423]

Product Sizes
1 mg
£1962.00
AB02389-10-3-BT-1MG
About this Product
SKU:
AB02389-10-3-BT
Additional Names:
MAPT; TAU; PHF-tau; MAPTL; MTBT1; TAU; PHF; Tau proteins; Alzheimer paired helical filaments; Paired helical filament-tau; Microtubule-associated protein tau; Neurofibrillary tangle protein; mAb 423; NOAL 6.423; NOAL 6/66.423.2
Application:
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS
translate.label.attr.clone:
MN423
Clonality:
Recombinant Monoclonal
Extra Details:
This is a reformatted chimeric human IgG1 Fc Silentâ„¢ antibody made using the variable domain sequences of the original mouse IgG2b format for improved compatibility with existing reagents, assays, and techniques.
Formulation:
PBS only.
Host:
Human
Immunogen:
The original antibody was generated by hyper-immunizing C3H mice with tangle-enriched fragments of the Alzheimer paired helical filaments core.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for the pronase-resistant core PHF and the 12 kDa tau fragment. It does not recognize normal full-length tau. It is also reported that this antibody specifically recognizes tau truncated at Glu391 on the C terminus side. The addition or removal of a single residue at the C-terminus abolishes immunoreactivity.
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies