Anti-PA anthrax [W1]
Product Sizes
200 ug
AB02352-10-3-200UG
About this Product
- SKU:
- AB02352-10-3
- Additional Names:
- protective antigen; PA; Anthrax toxins translocating protein; PA-83; PA83; anthrax toxin
- Application:
- Block/Inhibit/Neutralise, ELISA
- Buffer:
- PBS with 0.02% Proclin 300.
- translate.label.attr.clone:
- W1
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This full-length, chimeric human antibody was made using the variable domain sequences of the original scFv format, for improved compatibility with existing reagents, assays and techniques.
- Formulation:
- PBS with 0.02% Proclin 300.
- Host:
- Human
- Immunogen:
- The original scFv version of this antibody was isolated from a phage display library generated from immunized chimpanzees.
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Bacteria
- Shipping Conditions:
- Blue Ice
- Specificity:
- This antibody recognizes protective antigen (PA) of anthrax toxin. W1 antibody targets a conformational epitope formed by C-terminal amino acids 614-735 of PA (Chen et al., 2006; pmid: 16453257). W1 is thought to recognize the same neutralizing epitope as another anti-PA antibody W2 as they both competed with each other in binding to PA and have the same CDRs (Chen et al., 2006; pmid: 16453257). P
- Storage Conditions:
- 2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:Ab02352-10.3
