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Antibodies

Anti-Beta-actin [Fab 19, actin]

Product Sizes
1 mg
Was £1962.00 £1864.00
AB02221-10-3-BT-1MG
About this Product
SKU:
AB02221-10-3-BT
Additional Names:
Actin, cytoplasmic 1; Fab 19; Fab19; Fab 19, actin; Actin, cytoplasmic 1; ACTB; Beta-actin
Application:
ELISA, Immunofluorescence
Buffer:
PBS
translate.label.attr.clone:
Fab 19, actin
Clonality:
Recombinant Monoclonal
Extra Details:
This reformatted human antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques.
Formulation:
PBS only.
Host:
Human
Immunogen:
The original Fab version of this antibody was obtained by recombinant antibody phage display.
Isotype:
IgG1
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
This antibody is specific for the pointed end of actin filaments (Brawley et al, 2010; pmid: 21103060). Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (PubMed: 29581253). Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction.
Storage Conditions:
2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies